Tubulin



Tubulin (TUB) is a constituent of microtubules in eukaryotes. Microtubules are assembled from dimers of α-tubulin (TUBA) and β-tubulin (TUBB) bound to GTP. γ-tubulin (TUBG) is part of the nucleation of microtubules. Human TUB contains several numbered subtypes. FtsZ (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB. The images at the left and at the right correspond to one representative Tubulin, i.e. the crystal structure of Tubulin (1z5w).

Tubulin
3hkb, 3hkc, 3hkd, 3hke, 3n2g, 3n2k – TUBA+TUBB+stathmin-like protein B3 – sheep

2wbe – cTUBA1D+cTUBB2B+kinesin+AMPPNP – cow

3dco - cTUBA+cTUBB+kinesin-like NOD

1tvk - cTUBA+cTUBB+GDP+GTP+Epothilone A – electron crystallography

3iz0 - cTUBA+cTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy

3edl - cTUBA1D+cTUBB2B+kinesin motor domain

2xrp - cTUBA1D+cTUBB2B+doublecortin

3du7, 3e22, 1z2b, 1sa0, 1sa1 – cTUBA1C+cTUBB2B+stathmin-like protein B3

1ffx - cTUBA+cTUBB+stathmin-like protein B3

1jff - cTUBA+cTUBB

2p4n - hTUBA+hTUBB+kinesin heavy chain

3cb2 – hTUBG1+GDP

1z5v - hTUBG1+GTPgS

1z5w - hTUBG1+GTP

2hxf - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig

2hxh - pTUBA+pTUBB+kinesin-like KIF1A+ADP

1ia0 - pTUBA+pTUBB+kinesin-like KIF1A+ATP

1tub - pTUBA+pTUBB – electron diffraction

2bto – PdTUBA+thioredoxin 1 – Prosthecobacter dejongeii

2btq – PdTUBA+PdTUBB

FtsZ
2rhh, 2rhj – BsFtsZ+SO4 – Bacillus subtilis

2rhl - BsFtsZ+GDP

2rho - BsFtsZ+GDP+GTP-gamma-S

2vxy, 2vam – BsFtsZ

2ve8 – PaFtsZ gamma domain – Pseudomonas aeruginosa

2ve9 - PaFtsZ gamma domain+DNA

2vaw – PaFtsZ+GDP

1ofu - PaFtsZ+SULA

2r75 - AaFtsZ+8-morpholino-GTP – Aquifex aeolicus

2r6r - AaFtsZ

2q1x, 1rq2 - MtFtsZ+citrate – Mycobacterium tuberculosis

2q1y, 1rlu - MtFtsZ+GTP-gamma-S

1rq7 - MtFtsZ+GDP

2vap – MjFtsZ+GDP – Methancaldococcus jannaschii

1w58 - MjFtsZ+GMPCPP

1w59, 1fsz – MjFtsZ

1w5a - MjFtsZ+MgGTP

1w5b - MjFtsZ+GTP

1w5e, 1w5f – MjFtsZ (mutant)